Where does phentermine come from?

The nitro group is reduced with hydrogen gas on a Raney nickel catalyst. Phentermine (Adipex-P, Lomaira) is a prescription drug similar to amphetamine used to suppress appetite. It can help you lose weight by reducing hunger or making you feel satisfied longer. Phentermine is also available in combination with topiramate for weight loss (Qsymia).

Phentermine is used for a limited period of time to accelerate weight loss in overweight people who exercise and follow a low-calorie diet. Phentermine belongs to a class of medications called anorectics. Phentermine is an indirectly acting sympathomimetic agent that acts by releasing noradrenaline from the presynaptic vesicles of the lateral hypothalamus. This increase in the concentration of norepinephrine in the synaptic cleft results in the stimulation of beta2-adrenergic receptors.

3 Phentermine is classified as an indirect sympathomimetic because of the increase in the level of norepinephrine, dopamine and their indirect effect on serotonin, 10 Some reports have indicated that phentermine inhibits neuropeptide Y, which is one of the main signaling pathways for the induction of hunger, 8 This combined effect produces a continuous flight or fight response in the body that reduces the hunger signal, since this condition is based on the immediate need for energy, 8.

Colton Patchin
Colton Patchin

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